Tuberculosis (TB) remains one of the most persistent global health threats, primarily due to the ability of Mycobacterium tuberculosis (Mtb) to develop drug resistance and persist in the host for extended periods. The slow and grueling treatment process, often marred by relapse, underscores the urgent...
The ability to analyze individual cells allows scientists to uncover a wealth of information hidden in the cellular heterogeneity of tissues, leading to breakthroughs in understanding diseases and developing targeted treatments. However, despite the critical importance of this research, traditional methods of single-cell analysis, particularly...
The world of microorganisms is a complex and diverse realm that plays a vital role in various ecological, medical, and industrial processes. Understanding the intricate interactions and behaviors of different bacterial species can offer valuable insights into disease mechanisms, environmental dynamics, and even biotechnological...
In recent decades, microfluidic technology has witnessed remarkable advancements, offering novel ways to study cellular behavior and interactions under dynamic flow conditions. However, a significant gap has persisted in the field – the lack of automated and adaptable imaging and analytical tools to fully...
Single-cell RNA sequencing (scRNA-seq) has ushered in a new era of biological understanding by enabling the assessment of gene expression profiles at the individual cell level. This advancement has illuminated the complexities of cellular heterogeneity and functional diversity within biological systems. Yet, the pursuit...