"Current equipment and methods for preparation of radiopharmaceuticals for positron emission tomography (PET) are expensive and best suited for large-scale multi-doses batches. Microfluidic radiosynthesizers have been shown to provide an economic approach to synthesize these compounds in smaller quantities, but can also be scaled to...
Neuromuscular junctions (NMJs) are the synaptic junctions between motor neurons (MNs) and muscle fibres and are of crucial importance in delivering signals associated with motor activities. Therefore, defects in the motor neurons or disruption in the activity of NMJs can lead to neurodegenerative diseases such...
"Low-temperature biopreservation and 3D tissue engineering present two different routes towards eventual on-demand access to transplantable biologics, but recent advances in both fields present critical new opportunities for crossover between them. With help of microfluidics, in this work, we demonstrate sub-zero centigrade preservation and revival...
Myocardial infarction, commonly known as heart attack, causes a majority of cardiovascular disease (CVD) deaths which can be triggered by occlusion of the arteries. Finding new drugs to fight myocardial infractions requires accurate modelling of the process. In a recent article published in the lab...
Organ-on-a-chip systems are well established as 3D cell culture microfluidic models capable of recapitulating the in vitro microenvironment of the cells. Organ-on-a-chips can differ in various aspects such as having a monoculture/coculture, mechanical components, electrical elements for actuation or real-time readouts, etc. The combination of...