Droplet microfluidic Tag

Dropseq chips help researchers to study the transcriptional mechanisms of stress-related mood disorder major depression

Recent technological developments including microfluidics have facilitated genome-wide transcriptional profiling in select brain regions. These studies can be employed to discover correlations between altered transcriptional activity across brain regions with stress-related mood disordered leading to a better understanding of the molecular underlying driving mechanisms. Here,...

Microfluidic deep mutational scanning

Droplet microfluidics for deep mutational scanning

Caspases, a family of protease enzymes, play a crucial role in numerous biological processes, making them intriguing subjects of study for researchers. Understanding the structure, function, and regulation of caspases could pave the way for innovative therapeutic approaches. In a groundbreaking research study, scientists embarked...

Microfluidics: droplet based microfluidic generation of synthetic cells

Droplet microfluidics for assembly of endomembrane multicompartments

"By using electrostatic interactions as driving force to assemble vesicles, the droplet-stabilized method was recently applied to reconstitute and encapsulate proteins, or compartments, inside giant unilamellar vesicles (GUVs) to act as minimal synthetic cells. However, the droplet-stabilized approach exhibits low production efficiency associated with the...