The spatial organization and cellular microenvironment of the cells can be very important when it comes to RNA sequencing. Therefore, preserving the spatial organization of the cells and monitoring the changes in the cellular surrounding can be crucial for transcriptomic profiling. Droplet-based microfluidics is an...
Abstract "Cyanobacteria are fast-growing, genetically accessible, photoautotrophs. Therefore, they have attracted interest as sustainable production platforms. However, the lack of techniques to systematically optimize cultivation parameters in a high-throughput manner is holding back progress towards industrialization. To overcome this bottleneck, here we introduce a droplet-based microfluidic...
Cells live in a 3D environment and in-vitro studies that recapitulate this 3D environment can potentially better mimic the in-vivo conditions. Microfluidic chips and in particular droplet microfluidics have been promising in recent years for creating such 3D cell populations. For this week's research highlight,...
Abstract "The assembly of robust, modular biological components into complex functional systems is central to synthetic biology. Here, we apply modular “plug and play” design principles to a solid-phase protein display system that facilitates protein purification and functional assays. Specifically, we capture proteins on polyacrylamide hydrogel...
Being one of the most promising areas of microfluidics, droplet microfluidics has been widely used for high-throughput data acquisition in the past decade. However, the potential of droplet microfluidic devices for generating products (therapeutics, cosmetics, etc.) with real-life applications has not yet been fully explored....