Extracellular matrix (ECM) is the non-cellular element in the body that provides scaffolding as well as biochemical and biomechanical cues for the cells. Synthetic and natural ECMs are widely used in tissue and organ engineering applications. Although native tissues are often inhomogenous, many of the...
A group of researchers has now taken organ on a chips to a new level by developing a multiorgan system with circulating immune cells to mimic the immunosurveillance process. The results of this study that hinged upon a three organ microfluidic chip are reported in...
A chronic wound also called a non-healing wound is one that has failed to heal in an orderly and timely manner. If the wound does not heal in more than 8 weeks, it is considered a chronic wound. Several factors can contribute to the chronicity...
Personalized cancer therapy hinges upon predicting which patient is more responsive to specific therapies. It is based on the notion that the patient’s genotypes can affect the metabolism and drug toxicity while the tumor biomarkers are the indicators of the effectiveness of the treatment and...