"Microfluidic and mass spectrometry (MS) methods are widely used to sample and probe the chemical composition of biological systems to elucidate chemical correlates of their healthy and disease states. Though matrix-assisted laser desorption/ionization-mass spectrometry (MALDI)-MS has been hyphenated to droplet microfluidics for offline analyses, the...
Nature has always been a source of inspiration for us. Over years and years, nature has developed highly efficient mechanisms in living organisms that can light the way for designers and engineers. In this week’s research highlight, we are going to introduce a microfluidic chip...
"Cytotoxicity is a vital effector mechanism used by immune cells to combat pathogens and cancer cells. While conventional cytotoxicity assays rely on averaged end-point measures, crucial insights on the dynamics and heterogeneity of effector and target cell interactions cannot be extracted, emphasizing the need for...
Immunoassays are extensively used for quantifying biomarkers in clinical laboratories. This week’s research highlight focuses on a capillary-driven microfluidic device for rapid and sensitive one-step immunoassay published in Microsystems and Nanoengineering Journal in which gold nanorods were employed in the reaction chambers to enhance the...
Passive microfluidics, such as capillary-driven microfluidics, are excellent candidates for point-of-care applications. A passive method for delivering reagents to the device and performing reaction is advantageous in terms of cost and portability compared to active methods where an external means is employed for this purpose....