"To migrate efficiently to target locations, cells must integrate receptor inputs while maintaining polarity: a distinct front that leads and a rear that follows. Here we investigate what is necessary to overwrite pre-existing front-rear polarity in neutrophil-like HL60 cells migrating inside straight microfluidic channels. Using...
Malaria can introduce inclusion bodies in red blood cells which can be repaired in the spleen in a process called pitting. In the pitting process, a particle can get removed from the cytoplasm of the cells without destroying the cell itself. In this week's research highlight,...
"In stable environments, cell size fluctuations are thought to be governed by simple physical principles, as suggested by recent findings of scaling properties. Here, by developing a microfluidic device and using E. coli, we investigate the response of cell size fluctuations against starvation. By abruptly...
The circadian rhythm regulates many of the processes in the body and is crucial for general health. Dysfunctions in the circadian rhythm can be a risk factor leading to developing disorders including metabolic disorders. In this week's research highlight, we will introduce a recent article published...
"Messenger RNA (mRNA) delivery provides gene therapy with the potential to achieve transient therapeutic efficacy without risk of insertional mutagenesis. Amongst other applications, mRNA can be employed as a platform to deliver gene editing molecules, to achieve protein expression as an alternative to enzyme replacement...