Abstract "The patient population suffering from pancreatic ductal adenocarcinoma (PDAC) presents, as a whole, with a high degree of molecular tumor heterogeneity. The heterogeneity of PDAC tumor composition has complicated treatment and stalled success in clinical trials. Current in vitro techniques insufficiently replicate the intricate stromal...
One of the most promising applications of microfluidics technology has been proven to be the single-cell analysis. Hardly a week goes by without a new microfluidic development for microfluidic single-cell analysis. Over the nearly past decade, the field has accelerated at a high rate and...
The complex process of human pregnancy begins with the crucial step of embryo implantation. This involves the intricate interaction between the embryo's trophoblast cells and the maternal endometrium. A groundbreaking study published in Nature Communications has developed an advanced microfluidic chip, termed "implantation-on-a-chip", to simulate...
The study of the human brain, a complex and intricate organ, has always been a frontier in neuroscience. A recent study in this field has been presented in a study published in Lab on a Chip, where researchers have employed a microfluidic chip and construct...
Understanding the dynamic transitions of cell states has been a formidable challenge in cellular biology. Traditional methods have struggled to capture these intricate processes at a single-cell level. A recent study published in Cell introduces a new approach that leverages microfluidic technology to map transcriptomic...