The detection and analysis of small extracellular vesicles (sEVs), such as exosomes, has attracted significant attention due to their potential as circulating biomarkers for diseases, especially cancers and liver disorders. Yet, their small size and the complexity of blood plasma make direct detection difficult....
Magnetite nanoparticles (MNPs) have become valuable in areas ranging from environmental remediation and water treatment to medical diagnostics, electronics, and drug delivery systems. Their unique electrical and magnetic properties, combined with the ability to tailor their size and surface characteristics, make them a versatile...
Efficient delivery of RNA therapeutics hinges on the quality and consistency of lipid nanoparticles (LNPs) used to encapsulate mRNA. Traditional LNP synthesis methods, like pipette or vortex mixing, offer limited control and reproducibility, making it difficult to scale up for clinical use. While microfluidics...
Skin diseases like atopic dermatitis and psoriasis have been linked to gut health, yet the mechanisms behind this gut–skin connection remain poorly understood. Clinical evidence suggests that an imbalance in gut microbes (dysbiosis) can disrupt the intestinal barrier, leading to skin inflammation. However, it...
Red blood cell (RBC) deformability, the ability of RBCs to squeeze through tiny capillaries, is critical for oxygen delivery and cell longevity. While it is known that RBC deformability changes in many diseases, its behavior in iron deficiency (ID), particularly before the onset of...