Latest Research

Microfluidically-generated barcodes can help the battle against counterfeit products

Abstract

“A microfluidic platform for continuous synthesis of hydrogel microparticles with superparamagnetic colloids (SPCs) embedded at prescribed positions is described. The shape of the cross-linked microparticle is independently controlled by stop–flow lithography, whereas the position of trapped SPCs are dictated by virtual magnetic moulds made of 2D nickel patches facilitating magnetic trapping. The spatial positions of trapped SPCs collectively function as a binary code matrix for product authentication. Analytical and finite element methods are combined to optimize the trapping efficiency of SPCs by systematically investigating magnetic field microgradients produced by nickel patches. It is envisioned that the proposed magnetic microparticles will contribute to the development of soft matter inspired product quality control, tracking and anti-counterfeiting technologies.

“Scheme of the hydrogel microparticles synthesis. a) Solution containing polymer (PEGDA), photoinitiator and superparamagnetic colloids(SPCs) are pumped through a microfluidic channel. The VMMs placed on the bottom of the channel are magnetized on-demand to trap SPCs. UV light passing through a mask placed at the field stop of the microscope crosslinks the PEGDA to trap SPCs are designated positions. b) Illustration of four steps involved in synthesis from the top view. c) Hydrogel microparticles responds to the external magnetic field and moves from one channel wall to the other when a permanent magnet is brought in contact. Extracted from Movie S1 (Supporting Information). d–g) The microscopy pictures of microparticles of different shapes with SPCs placed at designated position. Their scale bars are all 25 µm. The mask used in synthesis of each particle is given along with a 3D illustration of the microparticle with embedded SPC.” Reproduced under Creative Commons Attribution 4.0 International License from Zhang, M.Warth, T.Boon, N.Demirörs, A. F.Eral, H. B.Microfluidic Synthesis of Hydrogel Microparticles with Superparamagnetic Colloids Embedded at Prescribed Positions for Anticounterfeiting ApplicationsAdv. Mater. Interfaces 2022, 2200899.

Figures and the abstract are reproduced from Zhang, M.Warth, T.Boon, N.Demirörs, A. F.Eral, H. B.Microfluidic Synthesis of Hydrogel Microparticles with Superparamagnetic Colloids Embedded at Prescribed Positions for Anticounterfeiting ApplicationsAdv. Mater. Interfaces 2022, 2200899. https://doi.org/10.1002/admi.202200899

Read the original article: Microfluidic Synthesis of Hydrogel Microparticles with Superparamagnetic Colloids Embedded at Prescribed Positions for Anticounterfeiting Applications

Pouriya Bayat

Published by
Pouriya Bayat

Recent Posts

A Micro-Organ Based Microfluidic Biosensor for Continuous Glucose Monitoring

Continuous glucose monitoring plays a central role in diabetes management, especially for patients with type…

March 9, 2026

Microfluidic Platform for Automated Organoid Culture and Longitudinal Imaging

Organoids have transformed in vitro tissue modeling, but their culture remains labor-intensive and variable. Manual…

February 28, 2026

Microfluidics for Integrated Spatial Transcriptomics and Protein Imaging on the Same Tissue Section

Spatial biology increasingly depends on technologies that can map gene expression and protein localization directly…

February 11, 2026

Microfluidic confinement reveals how bacteria cross one-micrometer-wide passages by flagellar wrapping

Microfluidic devices are widely used to replicate the physical constraints bacteria experience in natural and…

February 3, 2026

What Are Microfluidic Chips and Why They Matter in Canada

Microfluidic technology is changing how scientists work. It allows labs to run complex experiments using…

January 26, 2026

Machine Learning Meets Microfluidics to Decode Tumor-Neuron Electrical Crosstalk

Understanding how brain tumors interact with surrounding neural circuits is a significant challenge in neuro-oncology.…

January 26, 2026