The majority of microfluidic devices for Assisted Reproductive Technologies (ART) have aimed at enhancing sperm selection and analysis so far. A novel microfluidic chip, however, turns the page by offering a more efficient protocol for oocyte cryopreservation. The design rationale and performance of this microfluidic...
Researchers at the University of Leeds have developed a microfluidic chip for evaluating microbubble-assisted drug delivery to spheroids. The microfluidic device helped in creating a physiologically relevant in vitro condition for trapping and culturing tumor spheroids and subjecting them to microbubble guided drug delivery. The...
[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text]Tissue slices are precision-cut organ slices that are commonly used for metabolism and toxicity research due to their advantages such as maintaining cell-type diversity and preserving the organ cytostructure as well as the metabolic enzymes. A major issue is...
Microfluidic single-cell analysis platforms often take advantage of droplet microfluidic for encapsulating the cells within nL-pL droplets at high throughputs. Depending on the target outcome (genomics, epigenomics, transcriptomics, etc.), specific protocols are available for the tests.Cells in a culture can be highly heterogeneous and impose...
Undoubtedly, microfluidics has opened many new windows of opportunities for single-cell analysis. Droplet microfluidics, for example, has shown great promises for encapsulation, manipulation, and incubation of single-cells within nL-pL droplets at very high throughputs. As the field grows more and more methods get developed providing...