Since its emergence as a model organism, Caenorhabditis elegans (C. elegans), has appeared as a powerful means for studying a broad range of topics ranging from developmental biology to neuroscience. Having many genes with functional counterparts in humans, a transparent body, a short life cycle...
"Mammary tumor organoids have become a promising in vitro model for drug screening and personalized medicine. However, the dependency on the basement membrane extract (BME) as the growth matrices limits their comprehensive application. In this work, mouse mammary tumor organoids are established by encapsulating tumor...
The modularity of microfluidics enables microfabricated microfluidic chips to be either used as standalone systems or integrated as subsystems into more complex systems. In this week's research highlight, we will introduce one of these advanced technologies that employs a microfluidic pump for Marangoni propulsion in...
"Microfluidic and mass spectrometry (MS) methods are widely used to sample and probe the chemical composition of biological systems to elucidate chemical correlates of their healthy and disease states. Though matrix-assisted laser desorption/ionization-mass spectrometry (MALDI)-MS has been hyphenated to droplet microfluidics for offline analyses, the...
Nature has always been a source of inspiration for us. Over years and years, nature has developed highly efficient mechanisms in living organisms that can light the way for designers and engineers. In this week’s research highlight, we are going to introduce a microfluidic chip...