"Messenger RNA (mRNA) delivery provides gene therapy with the potential to achieve transient therapeutic efficacy without risk of insertional mutagenesis. Amongst other applications, mRNA can be employed as a platform to deliver gene editing molecules, to achieve protein expression as an alternative to enzyme replacement...
Lab on a chips are handheld microfluidic devices that are destined to integrate everyday lab routines such as DNA/RNA extraction, cell washing, cell sorting, etc. A crucial step that is required for diagnostics and point-of-care applications is nucleic acid amplification. In this week's research highlight, we...
"Microhabitat conditions determine the magnitude and speed of microbial processes but have been challenging to investigate. In this study we used microfluidic devices to determine the effect of the spatial distortion of a pore space on fungal and bacterial growth, interactions, and substrate degradation. The...
Bacteria is capable of sensing several environmental signals and propelling toward desirable niches for colonization. In this week's research highlight, we will introduce a simple microfluidic device that can be used to study the collective migration of E. coli published in Microsystems and Nanoengineering Journal. "In...
"Current equipment and methods for preparation of radiopharmaceuticals for positron emission tomography (PET) are expensive and best suited for large-scale multi-doses batches. Microfluidic radiosynthesizers have been shown to provide an economic approach to synthesize these compounds in smaller quantities, but can also be scaled to...