Abstract "Microfluidic designs are versatile examples of technology miniaturisation that find their applications in various cell biology research, especially to investigate the influence of environmental signals on cellular response dynamics. Multicellular systems operate in intricate cellular microenvironments where environmental signals govern well-orchestrated and robust responses, the...
Abstract "Oxidative stress is one of the key factors that leads to red blood cells (RBCs) aging, and impairs their biomechanics and oxygen delivery. It occurs during numerous pathological processes and causes anaemia, one of the most frequent side effects of cancer chemotherapy. Here, we used...
Biological systems are regulated through networks of highly complex behaviors. Bottom-up synthetic biology provides a means for deconvoluting the underlying architecture governing these network-based behaviours. Droplet microfluidics has been the gold standard for creating complex synthetic cells from the bottom-up. To better design such systems,...
Abstract "Infrared (IR) plasmonic nanoantennas (PNAs) are powerful tools to identify molecules by the IR fingerprint absorption from plasmon-molecules interaction. However, the sensitivity and bandwidth of PNAs are limited by the small overlap between molecules and sensing hotspots and the sharp plasmonic resonance peaks. In addition...
Fluid flow through a porous media can be seen in many biological and geological systems. The pores in porous media induce very complex fluid patterns that are sometimes overlooked. For example, the complex morphology in these systems is often associated with dead-ends resulting in a...