Drug delivery systems aim at the controlled release and targeted delivery of pharmaceutical compounds to the body. With the advances made in miniaturized devices and microfluidic flow control systems, we are steps closer to fully automated microfluidic drug delivery systems with real-time monitoring capabilities. For...
Abstract "Herpes simplex virus (HSV) naturally infects skin and mucosal surfaces, causing lifelong recurrent disease worldwide, with no cure or vaccine. Biomimetic human tissue and organ platforms provide attractive alternatives over animal models to recapitulate human diseases. Combining prevascularization and microfluidic approaches, we present a vascularized,...
The spatial organization and cellular microenvironment of the cells can be very important when it comes to RNA sequencing. Therefore, preserving the spatial organization of the cells and monitoring the changes in the cellular surrounding can be crucial for transcriptomic profiling. Droplet-based microfluidics is an...
Abstract "Cyanobacteria are fast-growing, genetically accessible, photoautotrophs. Therefore, they have attracted interest as sustainable production platforms. However, the lack of techniques to systematically optimize cultivation parameters in a high-throughput manner is holding back progress towards industrialization. To overcome this bottleneck, here we introduce a droplet-based microfluidic...
Scale-down reactors are essential for generating data on small scale and applying the observed improvement to larger and industrial scales. Microfluidic devices can be of great use in this sense. The reaction conditions could be carefully monitored while the volume of the reaction is scaled...