"Enzymes are represented across a vast space of protein sequences and structural forms and have activities that far exceed the best chemical catalysts; however, engineering them to have novel or enhanced activity is limited by technologies for sensing product formation. Here, we describe a general...
Wearable microfluidics is a hot topic of research with a promising potential for commercialization. Small and skin-friendly microfluidic devices can collect sweat from the skin and deliver it through a network of microfluidic channels to microchambers where they can undergo a chemical or biological reaction...
"To migrate efficiently to target locations, cells must integrate receptor inputs while maintaining polarity: a distinct front that leads and a rear that follows. Here we investigate what is necessary to overwrite pre-existing front-rear polarity in neutrophil-like HL60 cells migrating inside straight microfluidic channels. Using...
Malaria can introduce inclusion bodies in red blood cells which can be repaired in the spleen in a process called pitting. In the pitting process, a particle can get removed from the cytoplasm of the cells without destroying the cell itself. In this week's research highlight,...
"In stable environments, cell size fluctuations are thought to be governed by simple physical principles, as suggested by recent findings of scaling properties. Here, by developing a microfluidic device and using E. coli, we investigate the response of cell size fluctuations against starvation. By abruptly...