Archive for November, 2015

Rules of Thumb for Designing $1 Microfluidic Cartridges

Rules of Thumb for Designing $1 Microfluidic Cartridges

If your business plan requires your raw microfluidic chip’s cost remain under $1 for being competitive with existing solutions, then you need to plan for it early in the product development process. Unfortunately, too often we come across microfluidic device developers who learn heart-breaking, nasty surprises regarding scalability of their multi-million dollar prototypes.

uFluidix’s production team has put together a few rules of thumb for designing low-cost plastic microfluidic cartridges. If these restrictions are conflicting with your design requirements, then it is recommend to consult with a few lab-on-a-chip manufacturers soon.

Guideline for the design of low-cost plastic microfluidic chips.

  • Keep the width of features (channels, chambers, …) greater than 20um.
  • Use no more than two layers including one feature layer sealed by a flat substrate layer.
  • Keep aspect ratio (height/width) between 0.5 and 2.
  • Keep features only on one side of a layer.
  • Avoid hard-to-bond plastics such as olefin copolymers.
  • Avoid dissimilar layers.
  • Avoid need to micro alignment of layers.
  • Avoid drilled or punched ports. Instead, use side access.

Aarash Sofla, CEO, uFluidix